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Updated: Sep 9, 2025

Conversion of Human Induced Pluripotent Stem Cells iPSCs into Functional Spinal and Cranial Motor Neurons Using PiggyBac Vectors
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转换NKG2A表达驱动iPSC衍生的CARNK细胞的功能专业化

Minoru Kanaya, Camille Philippon, Herman Netskar

    bioRxiv : the preprint server for biology
    |September 2, 2025
    PubMed
    概括

    诱导多能干细胞 (iPSC) 衍生的自然杀手细胞 (iNK) 显示出强大的抗癌活性. 这些iNK细胞独立于抑制受体培养而成熟,显示出强大的免疫疗法效应器功能.

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    T Cell Activation and Clonal Selection

    T cells are integral to our adaptive immune system, recognizing and effectively responding to foreign antigens. T cell activation and clonal selection are pivotal in orchestrating this immune response. This article elucidates these mechanisms, detailing the roles of cluster of differentiation (CD) markers, major histocompatibility complex (MHC) molecules, costimulatory signals, and the process of clonal selection.
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