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Updated: Sep 9, 2025

A Method for Mouse Pancreatic Islet Isolation and Intracellular cAMP Determination
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自由脂肪酸受体4激动剂通过不同机制刺激小鼠与人群的胰岛素分泌

Laura Reininger, Muhammad H Rehman, Amelia Bouabcha

    bioRxiv : the preprint server for biology
    |September 2, 2025
    PubMed
    概括

    自由脂肪酸受体FFAR4的激活会增加胰岛素的分泌. 在小鼠中,这种作用通过间接的体位素抑制发生,而人类小岛则表现出直接的β细胞作用,突出了FFAR4疗法的物种差异.

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