相关实验视频

Updated: Jun 13, 2026

PAR-CliP - A Method to Identify Transcriptome-wide the Binding Sites of RNA Binding Proteins
12:24

PAR-CliP - A Method to Identify Transcriptome-wide the Binding Sites of RNA Binding Proteins

Published on: July 2, 2010

53.6K

对于染色体结合蛋白 PARP1 和 MeCP2,SELEX 确定了高亲和度的 RNA 标

Manana Melikishvili1, Kalpani De Silva2,3, Darrell P Chandler1

  • 1Department of Epigenetics, Van Andel Institute, Grand Rapids, MI 49503, USA.

iScience
|September 2, 2025
PubMed
概括

聚 (ADP- 核糖) 聚合酶1 (PARP1) 和甲基- CpG结合蛋白2 (MeCP2) 结合RNA. PARP1更喜欢富含关氨酸的RNA结构,而MeCP2则针对富含细胞因子的复杂RNA结构.

关键词:
生物化学应用分子相互作用生物分子的特性

更多相关视频

Sample Preparation for Mass Spectrometry-based Identification of RNA-binding Regions10:52

Sample Preparation for Mass Spectrometry-based Identification of RNA-binding Regions

Published on: September 28, 2017

8.2K
Exploring Sequence Space to Identify Binding Sites for Regulatory RNA-Binding Proteins11:34

Exploring Sequence Space to Identify Binding Sites for Regulatory RNA-Binding Proteins

Published on: August 9, 2019

6.7K

相关概念视频

Selectins01:25

Selectins

Cell adhesion is  an essential aspect of multicellularity. While stable cell interactions usually occur between cells of the same type, transient cell interactions occur between cells of different tissue types, such as between neutrophils and endothelial cells. Selectins are one class of cell adhesion molecules (CAMs) that bind carbohydrate ligands to form transient cell adhesion. They are rod-like proteins with a long extracellular part of variable length ending with the lectin domain, which...