睡眠不足对心率变化的影响:系统综述和元分析
Suling Zhang1, Xiaodan Niu1, Jinke Ma1,2
1Department of Public Basic Teaching, Xi'an Academy of Fine Arts, Institute of Body-Medicine Integration, Xi'an, China.
Frontiers in neurology
|September 2, 2025
概括
睡眠不足会损害心脏自主功能,降低心率变化 (HRV) 指数,如RMSSD,并增加交感活动指标 (LF,LF/HF). 这表明交感和副交感神经系统活动之间的平衡被破坏.
科学领域:
- 心脏病学
- 自主神经科学
- 睡眠医学
背景情况:
- 睡眠不足在苛刻的职业中很常见,
- 有关心血管疾病,情绪障碍和认知障碍.
- 心率变化 (HRV) 是神经神经系统功能的一个关键指标,其变化用于研究睡眠剥夺的影响.
研究的目的:
- 对睡眠不足对HRV的影响进行随机对照试验 (RCT) 的系统审查和元分析.
- 找出睡眠不足引起的心脏自主功能障碍的机制.
- 提供睡眠干预和心血管疾病预防策略.
主要方法:
- 在主要数据库 (PubMed,Embase等) 中进行系统的文献搜索 从2010年1月到2024年5月.
- 使用Cochrane偏差风险工具进行方法质量评估.
- 使用Review Manager 5.4和Stata 17.0进行的元分析.
主要成果:
- 这项研究包括了11个RCT,共有549名参与者.
- 睡眠不足显著降低了RMSSD (时间域) (p<0. 05).
- 睡眠不足显著增加了LF和LF/ HF (频率域) (p<0. 05),HF下降趋势不显著.
结论:
- 睡眠不足似乎会损害心脏自主功能,由RMSSD降低和LF/ HF升高表明.
- 研究结果表明,在睡眠剥夺后,共感活动占主导地位,并抑制了副共感活动.
- 建议在未来研究中使用标准化HRV测量方案来确认这些发现并探索机制.
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