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Updated: Sep 9, 2025

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与视网酸受体相关的孤儿受体α调节了记忆CD8+T细胞的旁观者激活

Zimeng Cai1, Mina Kozai2, Hironobu Mita1

  • 1Laboratory of Molecular Medicine, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan.

Frontiers in immunology
|September 2, 2025
PubMed
概括

与视网膜酸受体相关的孤儿受体α (RORα) 驱动记忆CD8+T细胞中的干扰素- (IFN-γ) 生产,通过旁观者激活增强早期宿主防御. 这揭示了感染或接种疫苗后提高免疫力的关键机制.

关键词:
一个T细胞旁观者激活免疫学记忆炎症的发生核接收器

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