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在VHH中对CDR3长度依赖模式的比较分析

Lu Zhang1, Tianyu Yang1, Yao Zhang1

  • 1Drug Discovery and Development, Shanghai Cell Therapy Group Co. Ltd., Shanghai, China.

Frontiers in immunology
|September 2, 2025
PubMed
概括

重链 (VHHs) 的可变域CDR3长度会影响它们的序列,结构和抗原结合. 观察到特定物种的差异,为向治疗提供了纳米体工程的信息.

关键词:
其他国家CDR3 的长度美国VHH-Ag 相互作用标志物一个纳米体其他类型单域抗体

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