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Updated: Sep 9, 2025

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在吸烟引起的COPD模型中,IL-17中和抗体减轻了功能和结构变化

Alyne Riani Moreira1, Camila Uchoa da Silva1, Leticia de Paula Costa Mattos1

  • 1Laboratory of Experimental Therapeutic (LIM 20), Division of Medicine - School of Medicine of Hospital das Clinicas HCFMUSP, Sao Paulo, Sao Paulo, SP, Brazil.

Frontiers in immunology
|September 2, 2025
PubMed
概括

在慢性阻塞性肺病 (COPD) 的小鼠模型中,用中和抗体阻断介素-17 (IL-17) 逆转了肺损伤和炎症. 这表明IL-17抑制剂可能为COPD患者提供治疗选择,即使在疾病发作后.

关键词:
慢性肺炎一个IL-17抑制剂适应性免疫反应呼吸机械学结构变化

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