灵活的双螺旋感应天线用于RFID血管流量传感
Yaneev Hacohen1, Steve J A Majerus1,2
1Department of Electrical, Computer, and Systems Engineering, Case Western Reserve University, Cleveland, OH 44106 USA.
IEEE sensors journal
|September 2, 2025
概括
这项研究介绍了一种使用无线电频率识别 (RFID) 技术的新型无电池植入式血流传感器. 这种灵活的袖子式传感器可以避免血液接触,减少并发症,并可实时监测血管动态.
科学领域:
- 生物医学工程
- 可植入的医疗器械
- 生物传感器
背景情况:
- 传统的血液接触传感器可能会导致结血和血小板沉积等并发症.
- 需要最小侵入性,可植入的传感器进行持续的血管监测.
- 现有的无线电频率识别 (RFID) 系统缺乏适用于血管的灵活,可植入的天线设计.
研究的目的:
- 开发一个无电池,可植入的血流传感器,
- 创建一个灵活的传感器系统, 尽量减少血液接触和相关的并发症.
- 为了实时监测血流和血管扩张.
主要方法:
- 在动脉,静脉或移植周围进行非侵入性植入的灵活的袖子式传感器架构.
- 设计了一种新的双螺旋天线 (DHA),用于灵活的RFID数据/电力传输.
- 制造了一种压电阻碳黑聚甲 (PDMS) 纳米复合材料柔性脉冲传感器 (FPS).
- 集成一个商业RFID芯片实时数据读取到外部收发器.
主要成果:
- 已证明可以在血管周围 (3-8毫米直径) 植入的功能 DHA 系统.
- 达到了0.007的典型合系数DHA在读数的5厘米.
- 在模拟狭窄的血管幻体中成功监测了200至400毫升/分钟的血液流量.
- 在12 Hz的采样速率下,能够检测低至10 mL/分钟的流量变化.
结论:
- 无电池,可植入的血流传感器系统为监测血管健康提供了有希望的解决方案.
- 新型灵活的DHA和FPS设计可轻松进行微创手术植入和可靠的血液流量测量.
- 这项技术有可能通过在关键血管应用中持续实时评估血流来改善患者的结果.
相关概念视频
01:03Anchoring Junctions
Anchoring junctions are multiprotein complexes that help cells connect to other cells and the extracellular matrix. Anchoring junctions are present on the lateral and basal surfaces of cells, providing strong and flexible connections. Focal adhesions are often formed due to cell interactions with the ECM substrata, which initiate signal transduction via kinase cascades and other mechanisms. Together, they provide stability and tissue integrity. There are three types of anchoring junctions:...
01:26Tension Response at Adherens Junctions
The adherens junctions that anchor cells together are multi-protein complexes that dynamically adapt to mechanical stimuli such as tensile forces and shear stress. Mechanosensory proteins in these junctions can sense such mechanical stimuli and undergo a shift in their conformation, resulting in an altered function — a process called mechanotransduction.
α-Catenin as a Mechanosensory Protein
The α-catenin of adherens junctions is an allosteric protein with three VH (vinculin homology) domains...
α-Catenin as a Mechanosensory Protein
The α-catenin of adherens junctions is an allosteric protein with three VH (vinculin homology) domains...
01:13Dense Connective Tissue
Dense connective tissue contains more collagen fibers than loose connective tissue. As a consequence, it displays greater resistance to stretching. There are two major categories of dense connective tissue— regular and irregular.
Dense Regular Connective Tissue
In dense regular connective tissue, fibers are arranged parallel to each other, enhancing its tensile strength and resistance to stretching in the direction of the fiber orientations. Ligaments and tendons are made of dense regular...
Dense Regular Connective Tissue
In dense regular connective tissue, fibers are arranged parallel to each other, enhancing its tensile strength and resistance to stretching in the direction of the fiber orientations. Ligaments and tendons are made of dense regular...