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Updated: Sep 9, 2025

Identification of Transcription Factor Regulators using Medium-Throughput Screening of Arrayed Libraries and a Dual-Luciferase-Based Reporter
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Published on: March 27, 2020

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SMURF1/2 是WNK1稳定的新型调节剂

Ankita B Jaykumar1, Sakina Plumber1, Derk Binns1

  • 1Department of Pharmacology, UT Southwestern Medical Center, Dallas, TX 75390, USA.

Kinases and phosphatases
|September 2, 2025
PubMed
概括

转化增长因子β (TGF-β) 信号传递对于血管修复至关重要. 这项研究揭示了蛋白质激酶WNK1 (无素1) 与E3无素连接酶如何相互作用以控制TGF-β信号和血管生成.

关键词:
其他:一个OSR1一个 SMURF1/2美国WNK1 其他

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