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在2型糖尿病患者中甲状腺功能障碍的频率和临床相关性:横断研究
Muhammad Zaryab Haider1,2, Muhammad Anees Ur Rehman3,2, Tayyaba Arooj Mufti4
1Cardiology, Rawalpindi Institute of Cardiology, Rawalpindi, PAK.
Cureus
|September 2, 2025
概括
甲状腺功能障碍,特别是甲状腺功能低下,在南亚的2型糖尿病患者中很常见. 它与较差的血糖控制和增加的微血管并发症有关,突出显示需要定期进行甲状腺查.
科学领域:
- 内分泌学
- 代谢疾病
- 糖尿病学
背景情况:
- 甲状腺功能障碍经常与2型糖尿病 (T2DM) 一起存在,加剧代谢问题和并发症风险.
- 南亚T2DM患者甲状腺功能障碍的患病率和类型尚不清楚.
研究的目的:
- 在T2DM患者中确定甲状腺功能障碍的频率和类型.
- 调查甲状腺功能障碍与人口,血糖,代谢和微血管因素之间的关联.
主要方法:
- 在巴基斯坦拉合尔进行了长达六个月的横截面研究.
- 评估了442名成年T2DM患者的临床数据,血糖控制 (HbA1c),代谢参数,微血管并发症和甲状腺特征.
主要成果:
- 甲状腺功能障碍普遍存在:23. 8% 甲状腺功能低下,14. 9% 亚临床甲状腺功能低下和 4. 5% 甲状腺功能过高.
- 甲状腺功能低下与年龄较大,体重指数较高,糖尿病持续时间较长,血糖控制较差 (HbA1c 9. 45±1. 64%) 和微血管并发症和脂质失调的增加有关.
- 甲状腺刺激激素 (TSH) 与年龄,BMI,糖尿病持续时间和HbA1c正相关.
结论:
- 甲状腺功能障碍,特别是甲状腺功能低下,在T2DM患者中很常见.
- 它与不利的人口和代谢特征以及较高的微血管并发症负担有关.
- 常规甲状腺查对于全面的糖尿病治疗至关重要.
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