组织工程手持式和机器人生物打印方法的最新进展
Meenakshi Kamaraj1, Nafiseh Moghimi1, Akshat Joshi1
1Terasaki Institute for Biomedical Innovation, Los Angeles, CA, USA.
概括
使用手持式或机器人打印机的现场3D生物打印提供了直接在患者身上再生受损组织的新方法. 这项技术在临床应用方面具有前景,但需要进一步开发以克服材料和工程方面的挑战.
科学领域:
- 生物医学工程
- 组织工程
- 复原医学
背景情况:
- 3D生物打印技术正在为患者的特定组织带来革命.
- 将3D生物打印从实验室转化为临床实践仍然是一个重大挑战.
研究的目的:
- 审查现场3D生物打印的最新进展,以进行组织再生.
- 分析用于临床翻译的手持式和机器人手臂辅助生物打印技术.
主要方法:
- 对现场3D生物打印的当前文献进行系统审查.
- 检查手持式和机器人手臂辅助生物打印系统.
- 生物材料,工程和临床整合方面的分析.
主要成果:
- 手持式和机器人手臂辅助生物打印可以在现场直接重建受损组织.
- 这些先进的技术提供了适应性和精确的解剖学匹配.
- 关键的挑战包括生物墨水配方,机械性能优化和细胞外矩阵模拟.
结论:
- 在现场3D生物打印具有重要的临床组织再生潜力.
- 解决当前生物墨水和制造方面的局限性对于成功的床翻译至关重要.
- 需要进一步的研究和开发才能充分实现这项技术的临床应用.
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