患有麻醉症患者的快速眼动相关阻塞性睡眠呼吸暂停的患病率和相关因素
Hamza O Dhafar1, Ali A Awadh2, Salih A Aleissi1
1The University Sleep Disorders Center, Department of Medicine, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Nature and science of sleep
|September 2, 2025
概括
阻塞性睡眠呼吸暂停 (OSA) 和REM睡眠相关的OSA (REM- OSA) 在麻醉症患者中很常见. 与对照组相比,REM- OSA的患病率更高,这表明需要进一步研究的潜在联系.
科学领域:
- 睡眠医学
- 神经学
- 肺病学
背景情况:
- 阻塞性睡眠呼吸暂停 (OSA) 是麻醉症的一种常见并发症.
- 关于快速眼动 (REM) 相关的OSA (REM- OSA) 在麻醉症中的数据有限.
- 了解REM-OSA的患病率和相关性对于诊断和治疗至关重要.
研究的目的:
- 在成年麻醉症患者中确定OSA和REM- OSA的患病率.
- 鉴定与睡眠障碍和REM-睡眠障碍相关的独立因素.
- 在麻醉症患者和没有麻醉症的对照人群中比较REM- OSA的流行率.
主要方法:
- 对前性收集的190名麻醉症患者 (NT1和NT2) 的回顾性分析.
- 使用多睡眠和多个睡眠延迟测试.
- 使用特定的呼吸暂停指数和REM睡眠持续时间标准来定义REM-OSA.
- 通过逻辑回归,将麻醉症患者与122名没有麻醉症的OSA对照进行了比较.
主要成果:
- 在55. 8%的麻醉症患者中诊断出OSA.
- 在26. 4%的麻醉症患者中存在REM- OSA,在2型麻醉症患者中略高 (30%) 比1型患者 (24%).
- 与对照组相比,REM- OSA显示了麻醉症患者患病率较高的趋势 (26. 4% vs 17. 2%,p=0. 09).
- 麻醉症中OSA的独立相关物包括男性性别,BMI和兴奋指数.
- REM- OSA与兴奋指数和REM睡眠时间独立相关.
结论:
- 在麻醉症患者中,OSA和REM-OSA是常见的并发症.
- 与对照组相比,REM- OSA在麻醉症患者中更为普遍.
- 需要对更大群体进行进一步的研究,以探讨麻醉症和REM-OSA之间的关联.
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