Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Disorders of the Skeletal Muscle01:28

Disorders of the Skeletal Muscle

The clinical conditions affecting the skeletal muscle tissue are broadly categorized as musculoskeletal and neuromuscular disorders.
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Experience-Dependent Plasticity of Periglomerular Cells in the Olfactory Bulb.

eNeuro·2026
Same author

Mixed squaramide thioesters as phosphate group analogues for non-competitive antagonists of the phospholipid-sensing G protein-coupled receptor GPR55.

RSC chemical biology·2026
Same author

Turnover of NESTIN-Negative Neural Progenitors Into NESTIN-Positive State by the Lack of JMJD3.

Genes to cells : devoted to molecular & cellular mechanisms·2026
Same author

A simple method that doubles learning speed for mice in touchscreen-based visual discrimination.

Scientific reports·2025
Same author

Application of Lentivirus Vectors to Adult Neurogenesis and Manipulation of Neural Stem Cells.

Methods in molecular biology (Clifton, N.J.)·2025
Same author

Misclassification in memory modification in <i>App<sup>NL-G-F</sup></i> knock-in mouse model of Alzheimer's disease.

eLife·2025

相关实验视频

Updated: May 12, 2026

Assessment of Murine Exercise Endurance Without the Use of a Shock Grid: An Alternative to Forced Exercise
07:52

Assessment of Murine Exercise Endurance Without the Use of a Shock Grid: An Alternative to Forced Exercise

Published on: August 14, 2014

19.4K

缺乏原发动性皮层的小鼠的自愿和强迫跑步能力

Ryusei Abo1, Mei Ishikawa1, Rio Shinohara1

  • 1Laboratory of Brain Development and Regeneration, Graduate School of Biostudies, Kyoto University, Kyoto, Japan.

Frontiers in neural circuits
|September 2, 2025
PubMed
概括

在小鼠中训练高速跑步时, 主要运动皮层并非必不可少. 然而, 移除它会影响自发的跑步行为.

关键词:
大脑皮层损伤发动机控制跑步轮跑步机

更多相关视频

Author Spotlight: Using the MouseWalker to Quantify Locomotor Dysfunction in a Mouse Model of Spinal Cord Injury
07:28

Author Spotlight: Using the MouseWalker to Quantify Locomotor Dysfunction in a Mouse Model of Spinal Cord Injury

Published on: March 24, 2023

3.3K
Tracking Individual Running Metrics in Mice Using a Voluntary Wheel Running Protocol that Minimizes Social Isolation
04:48

Tracking Individual Running Metrics in Mice Using a Voluntary Wheel Running Protocol that Minimizes Social Isolation

Published on: April 18, 2025

677

相关实验视频

Last Updated: May 12, 2026

Assessment of Murine Exercise Endurance Without the Use of a Shock Grid: An Alternative to Forced Exercise
07:52

Assessment of Murine Exercise Endurance Without the Use of a Shock Grid: An Alternative to Forced Exercise

Published on: August 14, 2014

19.4K
Author Spotlight: Using the MouseWalker to Quantify Locomotor Dysfunction in a Mouse Model of Spinal Cord Injury
07:28

Author Spotlight: Using the MouseWalker to Quantify Locomotor Dysfunction in a Mouse Model of Spinal Cord Injury

Published on: March 24, 2023

3.3K
Tracking Individual Running Metrics in Mice Using a Voluntary Wheel Running Protocol that Minimizes Social Isolation
04:48

Tracking Individual Running Metrics in Mice Using a Voluntary Wheel Running Protocol that Minimizes Social Isolation

Published on: April 18, 2025

677

科学领域:

  • 神经科学
  • 发动机控制
  • 动物的行为

背景情况:

  • 随意和强迫的运动控制涉及复杂的大脑区域协调.
  • 主要运动皮质在熟练跑步中的具体作用在很大程度上仍未确定.

研究的目的:

  • 研究主要运动皮层对于训练高性能跑步的必要性.
  • 要区分主运动皮层移除对自愿与强迫运动的影响.

主要方法:

  • 训练小鼠在轮子上进行高性能运行 (>10,000次/天).
  • 进行了双边皮质切除,包括主要运动皮质.
  • 对自愿和强制运行任务进行了测试.

主要成果:

  • 与虚假对照相比,皮层损伤延迟了自愿运行的恢复.
  • 在高速跑步机上跑步的性能没有受到皮质损伤的显著影响.
  • 皮质损伤的小鼠在跑步开始时自发性降低.

结论:

  • 主要运动皮质并不严格要求执行训练的快速运行.
  • 主要运动皮质在自发启动跑步行为中起着重要作用.