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用观察器装置进行过导管左心房塞后的特定年龄的结果

Ritu Yadav¹, Sia Savant², Meghana Prakash²

¹Midwestern University GME Consortium/Verde Valley Medical Center.

Journal of geriatric cardiology : JGC

|September 2, 2025

概括

老年患者 (75岁以上) 接受过导管左心房塞 (LAAO) 面临更高的重大心脏不良事件 (MACE) 风险,主要是由于死亡率增加. 这一年龄组的手术成功率也较低.

科学领域:

心脏病学
干预心脏病学
老年心脏病学

背景情况:

在心房的患者中,透导管左心房塞 (LAAO) 是抗凝药的替代方案.
对于LAAO在老年患者 (75岁以上) 的结果,数据有限.

研究的目的:

与年轻患者相比,评估75岁以上患者的LAAO结果.
在接受LAAO的老年人中确定特定的风险和程序成功率.

主要方法:

在2015年8月至2020年3月期间连续接受LAAO的723名AF患者的回顾性分析.
收集的数据包括临床,实验室,程序特征,药物和60天的结果.
主要结局是主要心脏不良事件 (MACE),包括死亡率,中风,出血和再入院.

主要成果:

75岁以上的患者的MACE显著增加 (17.1%对11.5%,P=0.03),主要是由于全因死亡率增加 (1.3%对0%,P=0.04).
在75岁以上的年龄组中,手术成功率较低 (92. 2% vs 96. 2%,P=0. 02).
年龄组之间中风,严重出血和再入院的发生率没有显著差异.

结论:

接受LAAO的老年患者 (> 75岁) 经历了更糟糕的结果,其特点是所有原因的死亡率更高,手术成功率更低.
需要进一步的前性研究来验证这些发现,并探索改善这一群体结果的策略.

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