功能性胃损失之前的身体膨胀演变在四牙形动物中:基因损失和快速演变的证据
Chang Liu1, Lei Lin1, Sheng Du1
1National Key Laboratory of Mariculture Biobreeding and Sustainable Goods, Yellow Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences, Qingdao, Shandong 266071, China.
Comparative biochemistry and physiology. Part D, Genomics & proteomics
|September 2, 2025
概括
在Tetraodontiformes物种中,胃消化的收性损失可能先于身体膨胀的演变. 这种"胃不起作用"的情况挑战了关于消化系统进化的先前假设.
科学领域:
- 进化生物学
- 基因组学
- 比较生理学
背景情况:
- 类动物表现出体内膨胀和酸性消化损失的趋同演变.
- 之前的理论将体内膨胀与胃消化损失联系在一起,
研究的目的:
- 研究四牙形动物胃消化损失的进化时间表.
- 检查跨融合血统的酸消化基因的遗传基础和进化模式.
主要方法:
- 分析了9个胃消化相关基因的存在,合成,基因表达和快速演变.
- 使用了四个家族的七个Tetraodontiformes物种的基因组资源.
- 具有和没有身体膨胀能力的物种的基因进化比较.
主要成果:
- 在一个谱系中,胃类物种 (包括Mola mola) 失去了或伪造了八个胃基因,保留了非功能性的pga1.
- 在另一种谱系中,Thamnaconus septentrionalis只保留了pga2,失去了pga1和pgc,在slc26a9和vsig1中发生了快速演变.
- 这些遗传模式表明胃消化损失发生在体内膨胀之前.
结论:
- 在Tetraodontiformes中,胃消化的收性损失早于身体膨胀的演变.
- 支持这些鱼类的"非功能性胃第一"进化模型.
- 突出了融合基因进化的作用,
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