在最大直径为30.0毫米或更小的肺固体腺癌中,放射性特征与通过空气传播之间的相关性
Pengfei Li1, Qi Sun1, Rowena Yip2
1Department of Radiology, Harbin Medical University Cancer Hospital, Harbin, Heilongjiang Province 150040, China; Department of Diagnostic, Molecular, and Interventional Radiology, Icahn School of Medicine at Mount Sinai, One Gustave Levy L. Place, New York, NY 10029, United States of America.
在小肺腺癌中,瘤通过空气空间 (STAS) 扩散的预测是多发性距离,血管嵌入和阻塞后变化. 手术前的CT导向活检没有显著影响STAS的存在.
科学领域:
- 肺病学
- 癌症学
- 放射学
背景情况:
- 通过空气传播的瘤是肺癌的关键预后因素.
- 使用手术前成像来预测小固体肺腺癌 (≤30.0毫米) 的STAS非常重要,但研究不足.
研究的目的:
- 在小型固体肺腺癌中确定基于人口和CT的STAS放射预测因子.
- 调查手术前CT导向活检与STAS存在的相关性.
主要方法:
- 对511名临床阶段IA固体腺癌 (≤30. 0毫米) 患者的回顾性分析.
- 使用统计测试对STAS阳性和STAS阴性组进行比较.
- 多变量分析以确定STAS的重要预测因素.
主要成果:
- 在12. 3%的患者中存在STAS.
- 显著的STAS预测因素包括距离腹膜,腹膜,远距离阻塞后变化和血管嵌入.
- 在手术前的CT导向活检和STAS之间没有发现显著的关联.
结论:
- 胸腔距离,血管嵌入和阻塞后变化等放射性特征是小肺腺癌中STAS的重要预测因素.
- 在手术前的CT导向活检似乎没有影响STAS,减轻了对其影响的担忧.
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