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由pH引起的形状变化和拉萨病毒尖峰复合物的抑制

Michael Katz1, Hadas Cohen-Dvashi1, Sarah Borni1

  • 1Department of Chemical and Structural Biology, Weizmann Institute of Science, 7610001 Rehovot, Israel.

Cell host & microbe
|September 2, 2025
PubMed
概括

拉萨病毒 (LASV) 的进入涉及pH依赖的尖端蛋白变化. 了解这些分子事件和受体相互作用是针对这种危险病原体开发新疗法的关键.

关键词:
拉萨病毒没有病毒单颗粒冷电磁体小分子药物尖峰复合体结构生物学病毒进入细胞

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