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Updated: Sep 9, 2025

Isolation of Primary Mouse Hepatocytes for Nascent Protein Synthesis Analysis by Non-radioactive L-azidohomoalanine Labeling Method
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Isolation of Primary Mouse Hepatocytes for Nascent Protein Synthesis Analysis by Non-radioactive L-azidohomoalanine Labeling Method

Published on: October 23, 2018

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通过 lysosome-PP2A 调节mTORC1信号转导的氨基酸依赖TSC2脱化

Takanori Nakamura1,2,3,4, Shigeyuki Nada5, Masaki Matsumoto6

  • 1Division of Cell Signaling and Molecular Medicine, Institute of Medical Science, The University of Tokyo, Tokyo, Japan nakamura.takanori.cb@ehime-u.ac.jp.

Life science alliance
|September 2, 2025
PubMed
概括

这项研究模拟了哺乳动物的拉巴胺复合物1 (mTORC1) 途径,揭示了氨基酸和生长因子的相互作用. 这表明mTORC1需要两个信号才能完全激活, 这对于理解代谢疾病至关重要.

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