1992年至2021年年龄段的人群中脑部和中枢神经系统癌症的全球负担:基于人口的研究
在PubMed上查看摘要
概括
此摘要是机器生成的。全球大脑和中枢神经系统 (CNS) 癌症的流行和发病率在20-64岁的成年人中从1992-2021年增加,而死亡率和DALY则下降. 在社会人口指数较高和较低的国家之间仍然存在显著的差异.
科学领域
- 流行病学
- 全球健康
- 癌症学
背景情况
- 大脑和中枢神经系统 (CNS) 癌症是一个重大的全球健康挑战.
- 了解中枢神经系统癌症的流行趋势和差异对于公共卫生干预至关重要.
研究的目的
- 从1992年到2021年,估计中枢神经系统癌症的全球,区域和国家负担,趋势和不平等.
- 分析人口影响和预测未来的癌症病例数量.
主要方法
- 基于人口的研究利用了2021年全球疾病负担和风险因素研究的数据.
- 对年龄标准化的流行,发病率,死亡率和因残疾而调整的寿命年 (DALYs) 的分析.
- 采用时间趋势分析,贝叶斯年龄周期队列建模,预测建模和时空高斯过程回归.
主要成果
- 从1992年到2021年,全球中枢神经系统癌症的流行率和发病率分别增加了 (AAPC为1. 04%和0. 23%).
- 年龄标准化的DALY和死亡率下降 (AAPC分别为- 0. 28%和- 0. 27%).
- 在年轻的成年人 (20 - 24岁) 中,患病率和发病率显著增加,而40 - 44岁的人群中,DALY和死亡率下降最多. 在SDI较低的国家发现患病率和发病率较高,与SDI较高的国家相比,DALY和死亡率继续上升.
结论
- 中枢神经系统癌症负担在不同社会人口统计指数 (SDI) 的国家之间存在显著的全球不平等.
- 这些差异凸显了对量身定制的临床指导方针和公平的全球卫生资源分配的迫切需要.
- 预计到2050年全球中枢神经系统癌症病例的增加突显了当前的公共卫生挑战.
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