内脏脂肪指数与心血管疾病之间的关联:系统审查和元分析
Rui Wang1, Jingxuan Liu1, Guowei Fang2
1The First Clinical College of Shandong University of Traditional Chinese Medicine, Jinan, China.
Nutrition, metabolism, and cardiovascular diseases : NMCD
|September 2, 2025
概括
高内脏脂肪指数 (VAI) 与心血管疾病 (CVD) 的风险增加有关,包括中风和死亡. VAI可能是心血管不良结果的重要风险标志物.
科学领域:
- 心脏病学
- 代谢健康
- 流行病学
背景情况:
- 内脏脂肪指数 (VAI) 是内脏脂肪积累的新标记.
- 内脏脂肪的积累与心血管疾病 (CVD) 的风险增加有关.
研究的目的:
- 探索VAI与多种心血管疾病之间的关联.
- 评估VAI作为潜在的心血管不良事件风险标志物.
主要方法:
- 对17项涉及824,268名参与者的观察队列研究进行了元分析.
- 在PubMed,Embase和Web of Science数据库中搜索相关研究.
- 使用随机效应模型并进行剂量反应分析的聚合效应大小.
主要成果:
- 高VAI与心血管疾病 (RR=1. 55),中风 (RR=1. 45),心血管死亡 (RR=1. 38) 和冠心病 (CHD) (RR=1.23) 的风险增加有关.
- 每增加0. 5单位的VAI与心血管疾病风险增加14. 4%,心血管死亡风险增加19%.
- 在VAI和中风风险之间观察到非线性关联.
结论:
- 高VAI是心血管疾病,中风,心血管死亡和心血管疾病的重要危险因素.
- VAI 呈现出与心血管疾病和心血管死亡事件的线性增加.
- VAI可能是心血管不良结果的有价值的临床风险标志物.
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