来自受感染和未受感染的猪伤口的质谱数据
Fredrik Forsberg1,2, Sven Kjellström3, Jitka Petrlova4,5
1Division of Dermatology and Venereology, Department of Clinical Sciences, Lund University, Lund, Sweden. fredrik.forsberg@med.lu.se.
Scientific data
|September 2, 2025
概括
这项研究提供了来自猪模型的性伤口流体数据,详细介绍了Staphylococcus aureus和Pseudomonas aeruginosa感染期间的变化. 可访问的数据集有助于进一步研究伤口感染.
科学领域:
- 生物化学
- 微生物学
- 蛋白质组学
背景情况:
- 使用质谱学的体学对于识别生物标志物和疗法非常有价值.
- 了解感染期间的伤口流体体的时间动态至关重要.
研究的目的:
- 提供一个全面的伤口流体基数据集.
- 分析受 Staphylococcus aureus 和 Pseudomonas aeruginosa 感染的猪伤口模型中的型.
主要方法:
- 样本:来自有S. aureus和P. aeruginosa感染的猪模型和未感染的对照组的时间性伤口液.
- 分析:依据数据获取模式进行提取,然后进行液态染色体双重质谱 (LC-MS/MS).
- 数据存储:Spectra和搜索的文件存储在在线存储库中以提供可访问性.
主要成果:
- 在受感染和未受感染的猪伤液中测定时体的特征.
- 对细菌感染动态相关的的鉴定.
- 为进一步的蛋白质组研究提供公开可访问的数据集.
结论:
- 这一数据集为调查伤口感染提供了宝贵的资源.
- 时间性体分析提供了关于伤口感染期间宿主-病原体相互作用的见解.
- 可访问的数据有助于发现新的生物标志物和治疗点.
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