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Updated: Sep 9, 2025

Detection of SARS-CoV-2 Neutralizing Antibodies using High-Throughput Fluorescent Imaging of Pseudovirus Infection
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不同的循环自身抗体与COVID-19住院和SARS-CoV-2中和活动有关

Rajesh Abraham Jacob1, Hannah O Ajoge1, Michael R D'Agostino2

  • 1Department of Medicine, McMaster University, Hamilton, ON, Canada.

Npj viruses
|September 2, 2025
PubMed
概括

SARS-CoV-2 感染可以引发自身免疫反应. 这项研究发现了与严重COVID-19住院相关的特定自身抗体,以及与中和SARS-CoV-2抗体相关的其他抗体.

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Antibody Actions01:26

Antibody Actions

Antibodies, or immunoglobulins, are critical players in the immune system's arsenal against invading pathogens. Produced by B cells and plasma cells, their primary role is to detect and bind to specific antigens, molecules found on the surface of pathogens like bacteria or viruses. Beyond antigen recognition, antibodies perform several vital functions that contribute to immune defense.
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Antibodies can bind to pathogens, preventing them from infecting host cells. This process...
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