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Updated: Sep 9, 2025

Quantitative Methods to Study Protein Arginine Methyltransferase 1-9 Activity in Cells
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Quantitative Methods to Study Protein Arginine Methyltransferase 1-9 Activity in Cells

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m1A甲基酶TRMT6通过以m1A/YTHDF2依赖的方式去甲基化SSTmRNA促进神经母细胞瘤的发展

Xinxin Zhang1, Huiran Lin1, Huimin Yin1

  • 1Department of Pediatric Surgery, Guangzhou Institute of Pediatrics, Guangdong Provincial Key Laboratory of Research in Structural Birth Defect Disease, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong, China.

British journal of cancer
|September 2, 2025
PubMed
概括

通过降低SSTmRNA稳定性,m1ARNA修饰调节器TRMT6促进神经母细胞瘤的进展. 针对TRMT6为神经母细胞瘤提供了潜在的新疗法.

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相关概念视频

Abnormal Proliferation02:23

Abnormal Proliferation

Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the...
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