淋巴瘤伪装成帕杰特骨病:一个罕见的诊断挑战
Irina D Sokolik1, Timothy A Damron2
1Upstate Department of Orthopedic Surgery, Upstate Medical University, 750 E Adams St, Syracuse, NY, 13210, USA. sokoliki@upstate.edu.
Skeletal radiology
|September 2, 2025
概括
帕杰特
科学领域:
- 整形医学
- 癌症学
- 放射学
背景情况:
- 帕杰特骨病 (PDB) 是一种常见的骨疾病,其特征是异常的骨重塑.
- 放射性发现通常是诊断性的,但可能与其他骨病理重叠.
- 像淋巴瘤这样的恶性瘤可能会在临床和放射学上模仿PDB.
研究的目的:
- 突出病理验证在异常呈现的帕杰特骨病的重要性.
- 为了区分帕杰特骨病与其他具有相似放射性外观的骨病变.
主要方法:
- 一个60岁的男性患有慢性下肢疼痛.
- 对左腿部病变进行放射和骨光学评估.
- 鉴于异常的X光检测结果,为组织病理学检查进行活检.
主要成果:
- 放射图显示帕杰特骨病, 骨上有火焰状的伤口.
- 在慢性淋巴细胞白血病 (CLL) 背景下,活检显示小淋巴细胞淋巴瘤 (SLL).
结论:
- 不典型的帕杰特病骨表现需要活检才能确诊.
- 通过病理验证可以避免错误诊断,确保适当的治疗.
- 在这种情况下,迅速诊断淋巴瘤导致有效的向治疗和放射治疗.
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