术前低温对手术部位感染风险的影响:元分析
Ruirong Chen1, Yingjie Du1, Lanyue Chen2
1Department of Anaesthesiology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
在外科手术期间出现的低温并未明确与手术部位感染 (SSI) 有关. 然而,在乳腺手术患者和体温降至35°C以下时,低温显著增加SSI风险.
科学领域:
- 医学研究
- 临床流行病学
- 手术结果
背景情况:
- 术后低温和手术部位感染 (SSI) 之间的关联尚不清楚.
- 了解这种联系对于改善患者安全和手术结果至关重要.
研究的目的:
- 澄清外科手术期间体温下降与SSI发生率之间的潜在关系.
- 确定这种关联更明显的特定患者群体或疾病.
主要方法:
- 综合分析了PubMed,Web of Science和Embase等数据库中的现有文献.
- 包括25项研究,共计28761名患者.
- 估计聚合风险比率和敏感性和子组分析的表现.
主要成果:
- 总体而言,在手术期间体温和SSI风险之间没有发现统计学意义上的关联 (OR,1. 39;95% CI,0. 98至1. 96).
- 在接受乳腺手术的患者中观察到显著更高的SSI风险 (OR,1. 97;95% CI:1. 21-3. 21).
- 当手术期间体温低于35°C时,SSI风险显著增加 (OR: 2.12,95% CI: 1. 42- 3. 16).
结论:
- 术后低温和SSI之间的联系并不确定,但在特定情况下是显著的.
- 乳腺手术患者和体温低于35°C的患者面临SSI的风险增加.
- 建议在未来进行研究,包括专注于乳房手术和标准化温度值的RCT,但由于异质性,需要谨慎解释.
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