在中风患者中压力高血糖和肺炎之间的关联:系统性审查和元分析
Xinyi Tu1,2, Chenghao Shi1, Jiajiang Jiang1
1Department of Nursing, The Second Affiliated Hospital of Zhejiang University School of Medicine, No. 88 Jiefang Road, Shangcheng District, Hangzhou, 310009, Zhejiang Province, China.
压力高血糖 (SH) 显著增加了中风后肺炎的风险. 与没有SH患者相比,SH患者患肺炎的几率是两倍的,这突显了患者护理的关键联系.
科学领域:
- 神经学
- 内分泌学
- 传染性疾病
背景情况:
- 肺炎是中风后的一个常见并发症.
- 压力高血糖 (SH) 是对中风的常见生理反应.
- 需要进一步调查SH与中风后肺炎的直接关系.
研究的目的:
- 系统地审查和分析观察性研究.
- 研究中风后压力高血糖和肺炎发生率之间的关联.
- 在中风患者中量化肺炎的风险.
主要方法:
- 在多个数据库 (PubMed,Embase等) 中进行全面的文献搜索 直到2024年7月.
- 包括12项观察性研究,评估中风患者和没有中风患者的肺炎发病率.
- 使用NOS评估的方法质量;通过随机效应模型估计的合并OR;遵循PRISMA指南.
主要成果:
- 肺炎的综合发病率为14. 4%.
- 在SH患者中,肺炎发病率显著增加 (OR: 2.01; 95% CI: 1. 72- 2. 34. P< 0. 01).
- 观察到显著的异质性;基于SH指标的元回归表明差异;证据质量被评为低.
结论:
- 压力高血糖与中风后肺炎的风险显著增加.
- 患有SH的中风患者患肺炎的几率大约是两倍.
- 由于研究的局限性和异质性,研究结果可能产生假设;建议谨慎解释.
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