患有全身性红斑性狼的个体中的跌倒:一项观察研究
Chelsea R Perfect1, C Barrett Bowling1, S Sam Lim2
1Duke University School of Medicine and Durham Veterans Affairs Geriatric Research Education and Clinical Center, Durham VA Medical Center, Durham, North Carolina.
ACR open rheumatology
|September 3, 2025
概括
在全身性红斑狼 (SLE) 患者中,跌倒很常见,失衡和虚弱是关键因素. 通过更好的SLE控制和药物评估可以降低跌倒风险.
科学领域:
- 关节病学
- 老年病学
- 公共卫生
背景情况:
- 系统性红斑狼 (SLE) 可能会加速衰老.
- 在SLE群体中,老年综合征如摔倒是研究不足的.
- 在易受伤害的患者群体中,跌倒构成重大风险.
研究的目的:
- 确定SLE患者中跌倒的发生率.
- 确定导致SLE人口下降的因素.
主要方法:
- 基于人口的447个SLE患者队列.
- 在过去的一年中自报的下降和促成因素.
- 多变量后勤回归以评估与跌倒的关联.
主要成果:
- 30. 7% 的SLE患者报告跌倒; 19. 2% 的患者跌倒了≥2次.
- 常见的原因包括失衡 (78.1%),滑倒/倒 (64.2%) 和虚弱 (53.3%).
- 较高的SLE活动,抑郁症状和增加跌倒风险的药物与更高的跌倒率有关.
结论:
- 在SLE患者中,无论年龄如何,跌倒都很普遍.
- 干预措施应集中在SLE疾病控制,物理治疗,心理健康查和药物管理上.
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