真实世界数据确定了淋巴瘤青少年和年轻成年患者的护理需求:一项匹配的队列研究
John Mariano1, Myla Strawderman2, Eric Snyder1
1Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, New York, USA.
Journal of adolescent and young adult oncology
|September 3, 2025
概括
青少年和年轻成年人 (AYA) 癌症患者,特别是淋巴瘤患者,有大量未满足的癌症护理需求. 电子医疗记录 (EMR) 可以有效地识别这些挑战,提供有针对性的干预措施和患者调查的信息.
科学领域:
- 癌症学
- 青少年和年轻人的医学 (AYA)
- 医疗信息学
背景情况:
- 青少年和年轻成年人 (AYA) 癌症患者面临与儿童和成年人不同的独特的癌症挑战.
- 国家指导方针强调了癌症患者在心理,身体和性/生殖健康方面的重大未满足需求.
- 识别这些护理差距对于开发有针对性的支持系统至关重要.
研究的目的:
- 探索使用电子病历 (EMR) 来确定AYA淋巴瘤患者的非癌症治疗领域的可行性.
- 在AYA淋巴瘤患者中比较这些非癌症领域的流行率和发病率与匹配的对照.
- 建立一个数据驱动的方法来解决AYA癌症护理的缺口.
主要方法:
- 一项追溯匹配队列研究,将AYA淋巴瘤患者 (2014-2020年) 与没有癌症的年龄/性别匹配对照患者进行比较.
- 在诊断前和诊断后的第一年使用了新的EMR评估工具来查询非癌症领域.
- 在淋巴瘤和对照组中比较了已识别的非癌症治疗领域的流行率和发病率.
主要成果:
- 与对照组相比,淋巴瘤患者在诊断前出现的慢性疼痛,止痛药使用和生育保育预约率较高.
- 在诊断后一年,淋巴瘤患者的焦虑,抗抑郁药物使用,阿片类药物滥用,慢性疼痛和生殖内分泌/不孕症预约率增加.
- 在诊断前和诊断后的慢性疼痛和止痛药使用中观察到显著的差异 (p < 0. 0001).
结论:
- 电子病历 (EMR) 提供了一种可行的方法来跟踪AYA癌症患者的机构非癌症护理领域.
- 数据可以指导特定机构的干预研究,以解决已发现的护理缺口.
- 预期患者调查可以设计以将EMR发现与患者报告的担忧相关联,从而增强整体护理.
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