慢性低水摄入与运动诱导的氧化应激和免疫细胞反应的改变有关:一个横截面研究
Minju Sim1, Wook Song2,3, Eun Young Choi4,5
1Seoul National University, Department of Food and Nutrition, Seoul, Republic of Korea.
Journal of the International Society of Sports Nutrition
|September 3, 2025
概括
慢性低水摄入会增加运动引起的氧化应激和细胞损伤. 保持足够的水分对于控制运动压力和预防不良免疫反应至关重要.
科学领域:
- 运动生理学
- 免疫学
- 营养科学
背景情况:
- 水分状态显著影响运动引起的氧化应激和体力表现.
- 虽然急性水合效应已知,但慢性低水摄入对氧化应激和运动期间免疫细胞变化的长期影响尚不清楚.
研究的目的:
- 研究习惯性低水摄入量与运动引起的氧化应激之间的关系.
- 根据慢性饮用水的模式,检查周围免疫细胞组成的变化.
主要方法:
- 评估参与者 (n=26,年龄19-29岁) 习惯饮用水,将他们分为饮用水量较高或饮用水量较低的人.
- 进行最大分级运动测试,测量血清活性氧代谢物 (ROM) 和生物抗氧化潜力 (BAP).
- 使用光激活细胞分类分析了包括CD4+,CD8+,CD20+,CD14+,CD11b+和Annexin V+在内的外周血液单核细胞 (PBMC).
主要成果:
- 与饮水量较高的人相比,饮水量较低的人的血清ROM水平较高.
- 虽然运动表现相似,但饮水量高的人在运动后血清BAP增加,与饮水量低的人不同.
- 在运动后,饮水量较低的患者体验到更大的PBMC细胞亡和免疫细胞分化 (CD11b+增加,CD14+减少).
结论:
- 习惯性低水摄入与运动期间的休息自由基副产品增加和抗氧化能力降低有关.
- 在低水饮者中,氧化还原平衡受损导致在运动压力时细胞损伤加快,免疫细胞反应发生改变.
- 为了减轻运动引起的氧化应激和防止细胞过度反应, 必须经常摄入足够的水分.
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