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Updated: Sep 9, 2025

Methods to Study Lipid Alterations in Neutrophils and the Subsequent Formation of Neutrophil Extracellular Traps
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Published on: March 29, 2017

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通过胆固醇代谢,PIM1调节CD4+T细胞子集与败血症相关的炎症失衡

Mei Liu1,2,3, Jia-Qi Wang1,2,3,4, Jia-Ning Wang1,2,3,4

  • 1National Clinical Research Center for Laboratory Medicine, The First Hospital of China Medical University, Shenyang, China.

mBio
|September 3, 2025
PubMed
概括

在败血症期间,Moloney小鼠白血病病毒1 (PIM1) 的前病毒集成部位在CD4+T细胞上调,导致免疫失衡. PIM1通过胆固醇代谢调节Th1,Th17和Treg细胞平衡,为败血症提供治疗点.

关键词:
CD4+ T 细胞在PIM1胆固醇新陈代谢炎症的发生感染性疾病

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