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[治疗内耳疾病的基因疗法:迈向未来的一步]

T G Markova^1,2,3, V V Bakhshinyan^2,3

¹Sverzhevsky Research Clinical Institute of Otorhinolaryngology, Moscow, Russia.

Vestnik otorinolaringologii

|September 3, 2025

概括

基因疗法正在听力学中出现,用于内耳疾病,临床试验正在进行中. 提高对遗传性听力损失和听力神经病谱障碍的认识和改进诊断工具至关重要.

科学领域:

遗传学与医学
听力学和耳鼻喉学

背景情况:

分子遗传学的进步和新的基因技术预示着医学新时代.
基因疗法正在成为一个重要的医学领域,
针对内耳疾病的创新治疗方案正在开发中,一些基因治疗方案正在临床试验中.

研究的目的:

在复杂的内耳疾病领域呈现基因治疗研究的现状.
突出科学与实践在治疗内耳病的交叉点.
强调医疗专业人员和患者对遗传性听力损失的提高意识的必要性.

主要方法:

对分子遗传学和基因治疗技术的当前进展进行审查.
对正在进行的内耳基因治疗临床试验的分析.
讨论遗传性听力损失和听力神经病谱障碍的诊断挑战.

主要成果:

基因疗法是治疗内耳疾病的前沿.
内耳基因疗法的临床试验正在进行中.
需要更好的诊断工具和更多的认识.

结论:

基因疗法对听力学和耳鼻喉学有很大的潜力.
进一步开发可靠的诊断工具对于早期检测至关重要.
让医生和患者了解遗传性听力损失对于利用新的治疗机会至关重要.

关键词:

其他:其他 TMC1 基因听力神经病的频谱障碍治疗内耳疾病的基因治疗遗传性听力损失其他药物

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