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Updated: May 4, 2026

Generation of Cationic Nanoliposomes for the Efficient Delivery of In Vitro Transcribed Messenger RNA
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Generation of Cationic Nanoliposomes for the Efficient Delivery of In Vitro Transcribed Messenger RNA

Published on: February 1, 2019

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通过PEGylated固体脂质纳米颗粒进行增强的mRNA和pDNA传递,具有最佳平衡的可离子化/化脂质含量

Nipuni Maniyamgama1,2, Ki Hyun Bae1, Jialing Lee1

  • 1Bioprocessing Technology Institute (BTI), Agency for Science, Technology and Research (A*STAR), 20 Biopolis Way, Centros #06-01, Singapore 138668, Republic of Singapore. yyyang@bti.a-star.edu.sg.

Journal of materials chemistry. B
|September 3, 2025
PubMed
概括

研究人员开发了用于增强基因传递的化脂质纳米颗粒 (PEG-iSLNs). 这些PEG-iSLN显示出卓越的mRNA转染和稳定性,显示出对体内应用的希望.

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