血液透析期间电动肌肉刺激对老年虚弱患者的影响:一个交叉随机对照试验
Yuta Suzuki1, Kentaro Kamiya2,3, Keika Hoshi4,5
1Center for Outcomes Research and Economic Evaluation for Health, National Institute of Public Health, 2-3-6 Minami, Wako, Saitama, 351-0197, Japan. szk.yutaf@gmail.com.
Journal of nephrology
|September 3, 2025
概括
在血液透析期间的电动肌肉刺激改善了脆弱的老年人的四头肌强度. 这种干预措施有望提高这一弱势群体的体能.
科学领域:
- 老年学
- 肝脏病学
- 康复医学
背景情况:
- 关于电动肌肉刺激 (EMS) 对接受血液透析的老年虚弱患者改善体能效果的证据有限.
- 之前的研究表明EMS对接受血液透析的中年患者有好处.
研究的目的:
- 研究肌肉电刺激 (EMS) 在老年肌肉虚弱患者中增强肌肉电动刺激的有效性.
- 评估EMS作为治疗性干预措施在这个特定的患者群体中的潜力.
主要方法:
- 这是一项交叉试验,涉及18名老年患者 (≥65岁) 患有虚弱 (SPPB评分为4-9),接受维持血液透析.
- 患者被随机分配,首先接受EMS或对照疗程,然后在5周的洗期后接受替代疗程.
- 在5周的血液透析期间,每周3次使用EMS30-40分钟.
主要成果:
- 治疗意向分析包括16名患者 (中位数为76岁,38%为男性,中位数为SPPB6).
- 在EMS期间,四肢同位体强度平均增加1. 5% (%DW).
- 相比之下,强度在对照期内下降了3. 6%DW的中位数 (P=0. 0027).
结论:
- 在老年患者中,肌肉电动刺激显著改善了四头肌的同位体强度.
- 这些发现表明,静脉透析EMS是改善血液透析的脆弱老年人身体表现的有益干预措施.
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