在患有血管的患者中对Tp- Te间隔的预测评估
Xiaomin Zhang1, Shuting Dai2, Haitao Wang2
1Department of Comprehensive Examination, Shanxi Cardiovascular Hospital, YiFen Street NO.18, Taiyuan, 030024, Shanxi, China. Zhang13593156371@163.com.
概括
测量心脏电活动的Tp-Te间隔可以预测血管 (VVS) 和其亚型. 较高的Tp- Te间隔表明VVS患者的头向上倾斜测试 (HUTT) 反应的可能性更高.
科学领域:
- 心脏病学
- 自主神经系统生理学
- 电心电图
背景情况:
- 血管 (VVS) 的特征是影响心脏电活动的自主失调.
- Tp-Te区间,代表跨壁再极化分散,是VVS的一个潜在指标.
- 评估Tp-Te可能有助于预测疑似VVS病例的头向上倾斜测试 (HUTT) 的阳性结果.
研究的目的:
- 在疑似VVS患者中,研究基线心电图间隔 (QT,QTc,Tp- Te) 与HUTT反应之间的关联.
- 确定Tp-Te间隔是否可以预测HUTT的阳性结果并区分VVS亚型.
主要方法:
- 179名疑似VVS的患者接受了HUTT.
- 患者分为HUTT阴性和HUTT阳性组 (血管抑制剂,心脏抑制剂,混合型).
- 在HUTT之前,对QT,QTc和Tp- Te间隔进行了基线12- 导电图分析.
主要成果:
- 与HUTT阴性患者相比,HUTT阳性患者的QT,QTc和Tp- Te间隔显著更高 (P< 0. 001).
- 与血管抑制剂小组相比,心脏抑制和混合型小组的Tp- Te间隔更高 (P < 0. 05).
- 一个Tp- Te间隔> 88毫秒预测了积极的HUTT (71. 7%的灵敏度,75. 9%的特异性),并且是一个比QT/ QTc更强的预测指标 (P < 0. 05). 预测的Tp- Te> 95毫秒心脏抑制/混合型反应 (敏感度为75%,特异性为57.1%).
结论:
- 由Tp- Te间隔表示的基线心肌再极化与VVS敏感性有关.
- 根据HUTT反应,Tp-Te间隔作为区分VVS亚型的新型,非侵入性指数.
- 基线Tp- Te间隔升高可能预测VVS患者的心脏抑制反应.
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