在化疗期间患有结肠直肠癌的患者的患者报告结果和身体组成变化:一项长度研究
Yuxuan Wu1,2, Xinyuan Yu1,3, Siting Huang4
1School of Nursing, Fujian Medical University, Fuzhou 350005, Fujian, China.
Journal of nursing management
|September 3, 2025
概括
接受化疗的结肠直肠癌 (CRC) 患者自我报告的结果恶化和肥胖指标增加,突出显示需要动态监测和支持性护理干预措施来改善身体组成和患者体验.
科学领域:
- 癌症学
- 临床营养
- 患者报告的结果
背景情况:
- 化疗显著影响结直肠癌患者的自我报告结果和身体组成.
- 了解这些变化对于优化患者护理和治疗效果至关重要.
研究的目的:
- 研究CRC患者在化疗期间自我报告的结果和身体组成的纵向变化.
- 在不同自我报告的患者轨迹子组中识别身体组成的差异.
主要方法:
- 在中国福州对201名CRC患者进行了长期研究.
- 使用患者报告的结果问卷,生物电阻分析,握力,功能测试和身体测量收集的数据.
- 分析早期,中期和晚期化疗阶段的趋势和亚组差异.
主要成果:
- 自我报告的结果最初恶化,然后在化疗期间恢复缓慢.
- 在治疗期间,肥胖指标 (体重,BMI,体脂) 显著增加 (p < 0. 05).
- 骨肌肉质量保持稳定 (p > 0. 05),但结果/ 症状轨迹有显著差异 (p < 0. 05).
结论:
- 对有中度至重度自我报告结果的CRC患者进行动态评估至关重要.
- 需要注意化疗期间的身体成分恶化,以优化患者的体验.
- 开发改善身体构成的干预措施可以提高个性化医疗服务.
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