预测PLR和血小板与LDL比率在静脉静脉支架后的静脉静脉支架
在PubMed上查看摘要
概括
此摘要是机器生成的。在动脉支架 (CAS) 之前,血小板与淋巴细胞的比率 (PLR) 和血小板/LDL水平可以预测支架静止症 (ISR). 这些生物标志物可能有助于识别CAS手术后中风复发风险较高的患者.
科学领域
- 血管医学
- 生物标志物发现
- 预防中风
背景情况
- 动脉支架 (CAS) 是通过恢复血液流动来预防缺血性中风的常见手术.
- 在CAS之后的静脉静脉复缩 (ISR) 会增加复发性缺血性中风的风险.
研究的目的
- 在CAS后确定ISR的预测生物标志物.
- 在预测ISR方面评估各种血液学比率的诊断性能.
主要方法
- 对221名CAS患者和145名健康对照者的回顾性分析.
- 分析中性细胞与淋巴细胞的比率 (NLR),血小板与淋巴细胞的比率 (PLR) 和其他血液学比率.
- 评估SII,SIRI和AISI指数;对PLR和血小板/LDL进行ROC曲线分析.
主要成果
- 在CAS患者中观察到NLR,PLR和其他比率的增加.
- 在初始CAS之前,增加的PLR和血小板/ LDL比率与ISR的发展有显著的关联.
- ROC分析表明PLR是一个强有力的预测指标,尽管敏感度适度.
结论
- 在第一次CAS操作之前确定的PLR和血小板/LDL比率是ISR的潜在预测生物标志物.
- 这些生物标志物可能有助于对ISR和随后中风复发风险的患者进行分层.
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