一次性内膜-肌膜癌:病例报告和文献综述
Dan Cheng1, Zhou Zhang2, Ye Zhu3
1Department of Blood Transfusion Medicine, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei 442000, P.R. China.
Experimental and therapeutic medicine
|September 3, 2025
概括
肺上皮细胞癌 (P-EMC) 是一种罕见的肺瘤. 这项案例研究强调了诊断方面的挑战,并提出了早期P-EMC的治疗方案.
科学领域:
- 肺病学
- 癌症学
- 病理学
背景情况:
- 肺上皮-肌上皮癌 (P-EMC) 是一种罕见的唾液腺类型的肺瘤.
- 由于P-EMC的罕见性和有限的长期数据,最优的治疗和随访仍未确定.
研究的目的:
- 报告一个罕见的肺上皮-肌上皮癌.
- 讨论P-EMC的诊断困难和潜在的治疗策略.
主要方法:
- 一个58岁的女性患有P-EMC的病例.
- 诊断最初是基于跨支气管活检的挑战;通过瘤切除术后的组织病理学证实.
- 治疗决定涉及多学科咨询和全面的分期扫描.
主要成果:
- 患者接受了左上叶切除术与中枢淋巴结解剖.
- 最终的病理学证实了P-EMC,患者在手术后5年内保持无病状态.
- 文献综述表明早期内支气管病变的替代治疗方法.
结论:
- 由于P-EMC的罕见性和双重表型,通过有限的活检样本进行准确的诊断是很困难的.
- 对于局部内支气管P-EMC (<2厘米),支气管镜干预或细分切除可能是替代方案.
- 对于较大的中央病变 (> 2厘米),为尽量减少发病率,偏好进行叶片切除或切除而不是肺切除.
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