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相关概念视频

MicroRNAs01:22

MicroRNAs

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MicroRNA (miRNA) are short, regulatory RNA transcribed from introns (non-coding regions of a gene) or intergenic regions (stretches of DNA present between genes). Several processing steps are required to form biologically active, mature miRNA. The initial transcript, called primary miRNA (pri-mRNA), base-pairs with itself, forming a stem-loop structure. Within the nucleus, an endonuclease enzyme, called Drosha, shortens the stem-loop structure into hairpin-shaped pre-miRNA. After the pre-miRNA...
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RNA interference (RNAi) is a cellular mechanism that inhibits gene expression by suppressing its transcription or activating the RNA degradation process. The mechanism was discovered by Andrew Fire and Craig Mello in 1998 in plants. Today, it is observed in almost all eukaryotes, including protozoa, flies, nematodes, insects, parasites, and mammals. This precise cellular mechanism of gene silencing has been developed into a technique that provides an efficient way to identify and determine the...
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[撤回] 通过微RNA-124抑制EMMPRIN抑制了质瘤的生长,侵袭和瘤性

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    此摘要是机器生成的。

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    科学领域:

    • 撤销通知

    背景情况:

    • 标识DOI的产品是10.3892/etm.2021.10362. 已经被撤回.

    研究的目的:

    • 正式宣布撤回指定的产品.

    主要方法:

    • 报纸已经开始撤回.

    主要成果:

    • 这篇文章不再被认为是科学记录的一部分.

    结论:

    • 读者应该忽略撤回文章中的所有发现和结论.