功能性消化不良 (FD) 患者的睡眠质量低下 (PSQ) 患病率:系统性审查和元分析
Rashmikaa Netyam1, Singam Shashank1, Chiranjeevee R Saravanan2
1General Medicine, Hampshire Hospitals, NHS Foundation Trust, Basingstoke, UK.
Annals of medicine and surgery (2012)
|September 3, 2025
概括
睡眠质量不佳影响了超过一半的功能性消化不良 (FD) 患者,他们比健康人更容易出现睡眠问题. 由于研究的局限性,需要进一步的研究来证实这些发现.
科学领域:
- 胃肠病学
- 睡眠医学
- 公共卫生
背景情况:
- 功能性消化不良 (FD) 是一种常见的胃肠疾病,其特征是腹部上部疼痛和腹.
- 睡眠质量差 (PSQ) 经常与功能性胃肠道疾病 (FGID) 相关,但对FD患者的数据有限.
- 这项研究旨在量化被诊断为FD的个体中PSQ的患病率.
研究的目的:
- 在诊断为功能性消化不良 (FD) 的患者中确定睡眠质量差 (PSQ) 的综合患病率.
- 评估与健康对照组相比,FD患者的PSQ风险.
- 确定影响FDPSQ的潜在调节因素.
主要方法:
- 在PubMed,Scopus和Web of Science进行了系统的文献搜索.
- 包括报告FD患者PSQ患病率或提供足够数据的研究.
- 使用元分析汇集流行数据并计算赔率比率,并对调节者进行元回归和子组分析. 使用道图表和埃格尔测试来评估出版偏差.
主要成果:
- 在2138名FD患者中,睡眠质量差的综合患病率为57. 2% (95% CI: 37% - 75. 2%),异质性很高 (I2 = 98. 4%).
- 在FD患者中,PSQ风险显著增加,概率为2. 39 (95% CI: 1. 86- 3. 06) 和低异质性 (I2 = 1.73%).
- 在聚合的流行率估计中发现了显著的出版偏差.
结论:
- 在功能性消化不良患者中,睡眠质量很差.
- 与健康人相比,FD患者睡眠不足的风险较高.
- 由于高异质性和出版偏差,研究结果应谨慎解释;未来的研究应解决混因素和标准化诊断.
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