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甲状腺原发性淋巴瘤:一个病例系列

Yousef Alalawi¹, Tahani N Alrashidi¹, Sarah Shafie¹

¹Department of Surgery, King Salman Armed Forces Hospital, Tabuk, SAU.

|September 3, 2025

概括

主性甲状腺淋巴瘤 (PTL),通常与哈西莫托甲状腺炎有关,通常呈现为快速增长的甲状腺质量. 核针活检对于诊断扩散性大B细胞淋巴瘤 (DLBCL) 是主要的PTL亚型至关重要.

科学领域:

癌症学
病理学
内分泌学

背景情况:

初级甲状腺淋巴瘤 (PTL) 是一种罕见的恶性瘤.
PTL经常与哈西莫托的甲状腺炎同时发生.
治疗PTL不同于其他甲状腺癌.

研究的目的:

调查PTL的临床表现.
评估PTL的诊断方法.
分析PTL的治疗策略.

主要方法:

七名PTL患者的回顾病例系列 (2017-2021年).
在临床表现,诊断和治疗方面收集的数据.
组织病理学检查证实了扩散型大B细胞淋巴瘤 (DLBCL).

主要成果:

7名患者 (5名女性,2名男性;平均年龄57. 8岁) 被诊断为PTL.
四名患者同时患有哈西莫托甲状腺炎.
快速扩大的甲状腺质量与压缩症状是常见的.
核针活检和手术切除均为诊断结果.
所有病例均为DLBCL.
在两个患者中观察到死亡率 (III和IV阶段).

结论:

快速增长的甲状腺质量与哈西莫托的甲状腺炎表明PTL.
DLBCL是主要的PTL亚型.
核针活检优于精针吸血细胞学 (FNAC) 进行诊断.
手术主要是诊断; 预后取决于疾病的阶段.

关键词:

化学疗法 (ct)核心针活检哈希莫托的甲状腺炎原发性甲状腺淋巴瘤 (ptl)辐射治疗 (rt)

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