在儿童中呈现为伪尾炎的Campylobacter感染:确定早期诊断的预测因素
Michael Schnapper1,2, Yaara Kahan2,3, Amir Klivitsky2,4
1Department of Pediatrics, E. Wolfson Medical Center, Holon, Israel.
Frontiers in pediatrics
|September 3, 2025
概括
坎皮洛巴克特肠炎可能模仿儿童的尾炎,导致CT扫描和抗生素使用增加. 主要预测因素包括发烧,低白细胞数和腹,有助于早期诊断.
科学领域:
- 儿童胃肠病学
- 传染性疾病
- 手术诊断
背景情况:
- 坎皮洛巴克特肠炎可能会出现模仿尾炎的症状,这会给诊断带来挑战.
- 这种被称为伪尾炎的表现可能会导致更多的诊断成像和治疗.
研究的目的:
- 在儿童中表现为伪尾炎的Campylobacter肠炎的特征.
- 确定坎皮洛巴克特伪尾炎的特异性预测因素.
主要方法:
- 对因疑似尾炎而住院的儿童 (< 18 岁) 进行回顾性多中心研究 (2014 - 2023 年).
- 伪尾炎的病例与确诊尾炎的对照病例相匹配.
- 用多变量逻辑回归分析来确定预测因素.
主要成果:
- 55个伪尾炎病例与110个尾炎病例进行了比较.
- 在伪尾炎组中观察到较高的计算机断层扫描率 (38% vs. 20%) 和广泛抗生素的使用率 (34. 5% vs.
- 伪尾炎的独立预测因素包括发烧,WBC<12,000/μl,中腔淋巴瘤病变/尾炎的超声波迹象,无超声波尾炎症状,腹和年龄>14岁.
结论:
- 坎皮洛巴克特伪尾炎导致严重的诊断挑战,包括CT成像的增加和不必要的抗生素使用.
- 鉴定特定的预测因子可以帮助临床医生在疑似尾炎的情况下怀疑Campylobacter肠炎.
- 通过识别这些预测因素,可以促进早期的分子诊断和改善患者护理.
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