超加工食品和儿童全身炎症的标志物
Camila Awad1,2,3, Paola Rubilar3, Macarena Hirmas-Adauy3
1Universitat Pompeu Fabra Barcelona Spain.
Food science & nutrition
|September 3, 2025
概括
超加工食品 (UPF) 的摄入可能与儿童的炎症有关. 这项研究表明,与年轻人群体的UPF消费相关的不良健康影响的潜在机制.
科学领域:
- 儿童营养
- 炎症和免疫学
- 公共卫生
背景情况:
- 全球越来越多的儿童食用超加工食品.
- 现有研究将UPF与成年人的不良健康结果联系起来,但对儿童的机制不太了解.
- 系统性炎症是UPF摄入与儿童健康状况不佳的潜在途径.
研究的目的:
- 研究小学儿童的UPF消费与全身炎症标志物之间的关联.
- 探索UPF与炎症关系中的潜在年龄相关差异.
- 确定炎症是UPF对儿童健康影响的可能机制.
主要方法:
- 在智利阿里卡对450名7-10岁儿童进行的横截面研究.
- 使用44项食物频率问卷和NOVA分类量化UPF摄入量为%kcal.
- 使用多重线性回归测量和分析细胞因子水平 (IL-6,IL-8,IL-10,IL-12,IL1β,TNF-α),调整为共变量.
主要成果:
- 平均UPF摄入量为总能量的29%.
- 在UPF摄入量和IL-1β水平之间观察到一种暗示性趋势 (趋势p=0. 01).
- 在老年儿童 (≥9岁,p相互作用=0. 02) 中发现了UPF摄入量与IL-6的相关性.
结论:
- 在学龄儿童中,UPF摄入量与特定的细胞因子水平存在潜在关联.
- 炎症可能是UPF消费与儿童健康不良影响的关键机制.
- 需要进一步的研究来阐明UPF在儿童群体的长期健康影响.
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