Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Determining the Plane of Cell Division02:13

Determining the Plane of Cell Division

3.4K
Positioning the cell division plane is a critical step during development and cell differentiation, particularly during mitosis when the plane is essential for determining the size of the two daughter cells. The cell division plane is perpendicular to the plane of chromosome segregation, but different types of organisms have different cell division mechanisms to suit their morphology and function. 
Animal cells
In animal cells, the cleavage furrow forms along the plane of cell division...
3.4K
Non-equilibrium in the Cell01:16

Non-equilibrium in the Cell

4.8K
An important concept in studying metabolism and energy is that of chemical equilibrium. Most chemical reactions are reversible. They can proceed in both directions, releasing energy into their environment in one direction, and absorbing it from the environment in the other direction. The same is true for the chemical reactions involved in cell metabolism, such as the breaking down and building up of proteins into and from individual amino acids, respectively. Reactants within a closed system...
4.8K
Cells Coordinate Growth and Proliferation02:36

Cells Coordinate Growth and Proliferation

4.6K
Cell size is a significant factor impacting cellular design, function, and fitness. There exists some internal coordination by which cells double their masses before division, thus, achieving homeostasis. Coordination between cell growth and proliferation depends on the checkpoints in between cell cycle phases. Loss of coordination or failure in the checkpoint mechanism can drive the cell to uncontrolled growth and loss of cellular function. Like dividing cells that coordinate cellular growth,...
4.6K
Molecular Factors Affecting Cell Division01:27

Molecular Factors Affecting Cell Division

3.3K
Several external and internal factors influence the initiation and inhibition of cell division. For instance, the death of nearby cells or the release of human growth hormone (hGH) promotes cell division. In contrast, lack of hGH or crowding of cells can inhibit cell division.
Several proteins function as internal regulators to ensure each cell cycle stage is completed faithfully before proceeding to the next. Regulator molecules may act directly or influence the activity or production of other...
3.3K
Non-nuclear Inheritance01:29

Non-nuclear Inheritance

21.7K
Most DNA resides in the nucleus of a cell. However, some organelles in the cell cytoplasm⁠—such as chloroplasts and mitochondria⁠—also have their own DNA. These organelles replicate their DNA independently of the nuclear DNA of the cell in which they reside. Non-nuclear inheritance describes the inheritance of genes from structures other than the nucleus.
21.7K
Replicative Cell Senescence02:15

Replicative Cell Senescence

3.7K
Replicative cell senescence is a property of cells that allows them to divide a finite number of times throughout the organism's lifespan while preventing excessive proliferation. Replicative senescence is associated with the gradual loss of the telomere — short, repetitive DNA sequences found at the end of the chromosomes. Telomeres are bound by a group of proteins to form a protective cap on the ends of chromosomes. Embryonic stem cells express telomerase — an enzyme that adds...
3.7K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

A transcription factor-sRNA-mediated double-negative feedback loop confers pathogen-specific control of quorum-sensing genes.

mBio·2026
Same author

Predicting mosquito flight behavior using Bayesian dynamical systems learning.

Science advances·2026
Same author

A transcription factor-sRNA-mediated double-negative feedback loop confers pathogen-specific control of quorum-sensing genes.

bioRxiv : the preprint server for biology·2025
Same author

Capillary interactions drive the self-organization of bacterial colonies.

Nature physics·2025
Same author

A pyrenoid-based CO2-concentrating mechanism can be effective and efficient even under scenarios of high membrane CO2 permeability.

Plant physiology·2025
Same author

Analysis of gene expression within individual cells reveals spatiotemporal patterns underlying Vibrio cholerae biofilm development.

PLoS biology·2025

相关实验视频

Updated: Sep 9, 2025

Tracking and Quantifying Developmental Processes in C. elegans Using Open-source Tools
10:41

Tracking and Quantifying Developmental Processes in C. elegans Using Open-source Tools

Published on: December 16, 2015

9.0K

跨物种细胞分裂动态中的非线性记忆

Shijie Zhang1, Chenyi Fei1, Jörn Dunkel1

  • 1Department of Mathematics, Massachusetts Institute of Technology, Cambridge, MA 02139.

Proceedings of the National Academy of Sciences of the United States of America
|September 3, 2025
PubMed
概括
此摘要是机器生成的。

细胞大小的控制是平衡的关键. 新模型显示,细胞分裂往往取决于复杂的非线性记忆,挑战细菌和酵母中的现有线性模型.

关键词:
贝叶斯推理细胞分裂细胞内存随机动态

更多相关视频

Live Cell Imaging to Assess the Dynamics of Metaphase Timing and Cell Fate Following Mitotic Spindle Perturbations
07:14

Live Cell Imaging to Assess the Dynamics of Metaphase Timing and Cell Fate Following Mitotic Spindle Perturbations

Published on: September 20, 2019

8.3K
Visualizing Neuroblast Cytokinesis During C. elegans Embryogenesis
09:52

Visualizing Neuroblast Cytokinesis During C. elegans Embryogenesis

Published on: March 12, 2014

12.0K

相关实验视频

Last Updated: Sep 9, 2025

Tracking and Quantifying Developmental Processes in C. elegans Using Open-source Tools
10:41

Tracking and Quantifying Developmental Processes in C. elegans Using Open-source Tools

Published on: December 16, 2015

9.0K
Live Cell Imaging to Assess the Dynamics of Metaphase Timing and Cell Fate Following Mitotic Spindle Perturbations
07:14

Live Cell Imaging to Assess the Dynamics of Metaphase Timing and Cell Fate Following Mitotic Spindle Perturbations

Published on: September 20, 2019

8.3K
Visualizing Neuroblast Cytokinesis During C. elegans Embryogenesis
09:52

Visualizing Neuroblast Cytokinesis During C. elegans Embryogenesis

Published on: March 12, 2014

12.0K

科学领域:

  • 定量生物学
  • 细胞生物学
  • 动态系统

背景情况:

  • 细胞大小平衡对于细胞功能至关重要,并依赖于受调节的生长和分裂.
  • 先进的成像 (例如,母机) 能够跨代追踪细胞大小的动态.
  • 目前对动态系统框架内的细胞大小控制机制的理解是有限的.

研究的目的:

  • 开发和应用一种用于推断细胞生长和分裂的随机微分方程模型的新框架.
  • 研究非线性记忆效应在细胞分裂时间中的作用.
  • 量化评估现有的细胞平衡模型 (测量器,加量器,定时器).

主要方法:

  • 从实验时间序列数据中推断随机微分方程模型的Poisson噪声.
  • 波桑强度的参数化,包括细胞大小和祖先历史,以捕捉非线性记忆.
  • 该框架应用于大肠杆菌,细菌,虫和虫的细胞大小轨迹.

主要成果:

  • 开发的框架成功地推断了随机细胞生长和分裂的定量模型.
  • 分析显示多个生物体的细胞分裂时间通常涉及显著的非线性记忆元件.
  • 在许多情况下,流行的线性记忆模型 (计量器,加量器,计时器) 发现不足.

结论:

  • 现有的细胞平衡的线性记忆模式可能需要重新评估和概括.
  • 非线性记忆在不同物种的细胞分裂中起着重要作用.
  • 推断框架广泛适用于各种科学领域的随机跳跃过程.