抗血管内皮生长因子治疗的第3期和第4期状细胞视网膜病变改善了解剖和视觉结果
Jennifer I Lim1, Ogugua N Okonkwo2, Sally S Ong3
1Department of Ophthalmology, University of Illinois at Chicago and Illinois Eye and Ear Infirmary, Chicago, IL.
Retina (Philadelphia, Pa.)
|September 3, 2025
概括
内抗血管内皮生长因子 (抗VEGF) 疗法有效治疗状细胞增殖视网膜病变 (PSR),改善视力并控制大多数患者的病情. 这种治疗为治疗PSR晚期提供了一个有前途的选择.
科学领域:
- 眼科 眼科
- 血管生物学
- 视网膜疾病
背景情况:
- 状细胞增殖视网膜病变 (PSR) 是状细胞疾病的一种危及视力的并发症.
- 在PSR的高级阶段 (3和4),对视力保护构成重大挑战.
研究的目的:
- 评估内抗血管内皮生长因子 (抗VEGF) 治疗治疗第3期和第4期状细胞视网膜病变 (PSR) 的有效性.
主要方法:
- 对接受了静脉内抗VEGF注射的3期和4期PSR患者进行了回顾性审查.
- 在治疗后分析了解剖学和视觉敏度的结果.
主要成果:
- 大多数眼睛 (93%) 在不需要手术的情况下控制了PSR.
- 大多数治疗眼睛的视力在一个月内改善或保持稳定.
- 与第三阶段的眼睛相比,第四阶段的PSR眼睛的视力明显改善.
结论:
- 静脉内抗VEGF治疗是晚期PSR的可行治疗方法,导致新血管和玻璃体出血的回归.
- 这种治疗显示出良好的安全性,没有报告的内炎病例.
- 有或没有激光的抗VEGF治疗在PSR管理中提供了可比的视觉结果.
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