肉类摄入量与乳腺癌风险
Hyobin Lee1, Woo-Kyoung Shin2, Katherine De la Torre3
1Department of Preventive Medicine, Seoul National University College of Medicine, Seoul, South Korea; Integrated Major in Innovative Medical Science, Seoul National University Graduate School, Seoul, South Korea.
Clinical nutrition (Edinburgh, Scotland)
|September 3, 2025
概括
在女性中,加工肉食增加了57%的乳腺癌风险. 另一方面,牛肉的摄入可能会降低乳腺癌的风险,尤其是在没有家族病史的年轻女性中.
科学领域:
- 流行病学
- 营养科学
- 癌症学
背景情况:
- 肉类消费与乳腺癌风险之间的联系尚不完全清楚.
- 这项研究调查了特定肉类与乳腺癌发病率之间的关联.
研究的目的:
- 研究加工肉类和牛肉摄入量与乳腺癌风险之间的关系.
- 根据肉类消费模式,确定潜在较高或较低风险的女性子组.
主要方法:
- 一项前性队列研究,涉及40至69岁的71,264名女性,来自健康检查者-Gem (HEXA-G) 研究.
- 使用考克斯比例危险模型来估计乳腺癌风险的危险比率 (HRs) 和95%置信区间 (CI).
- 癌症诊断通过韩国中央癌症登记处追踪到2018年12月.
主要成果:
- 每周加工肉类的消费与乳腺癌风险增加了57% (HR=1.57).
- 这种关联在50岁以下的女性中更强烈,没有家族病史,没有定期运动,没有饮酒,BMI< 25 kg/ m2.
- 牛肉摄入量显示乳腺癌风险可能降低 (HR=0.82每月≥2份).
- 饮酒也与乳腺癌风险降低有关,特别是在没有家族病史或定期炼的女性中.
结论:
- 加工肉类的摄入与乳腺癌的风险增加有关.
- 牛肉消费可能与乳腺癌的风险降低有关.
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