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Updated: Sep 9, 2025

Immunohistochemical Visualization of Hippocampal Neuron Activity After Spatial Learning in a Mouse Model of Neurodevelopmental Disorders
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Published on: May 12, 2015

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NRF2 缺乏与海马中的突触变化和以太结合的脂失衡有关

Daniel Carnicero-Senabre1, Mariana A Barata2, José Jiménez-Villegas1

  • 1Department of Biochemistry, Medical College, Autonomous University of Madrid (UAM), Madrid, Spain. Instituto de Investigaciones Biomédicas Sols-Morreale (CSIC-UAM), Madrid, Spain; Instituto de Investigación Sanitaria La Paz (IdiPaz), Madrid, Spain; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain.

Redox biology
|September 3, 2025
PubMed
概括

核红素因子2 (NRF2) 缺乏通过改变脂质代谢,导致突触损失,从而损害突触完整性. 激活NRF2可以防止这种衰退,为神经退行性疾病提供治疗潜力.

关键词:
6-MSITC 公司乙脂类脂质组学其他类型突触 突触

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