训练营翻译:一种增加人类乳头瘤病毒 (HPV) 接种疫苗的新方法
Sean T O'Leary1, Amanda Skenadore2, Bridget S Mosley2
1ACCORDS, University of Colorado Anschutz Medical Campus, United States; Department of Pediatrics, University of Colorado Anschutz Medical Campus, United States.
Vaccine
|September 3, 2025
概括
培训营翻译 (BCT) 在儿科诊所显著增加了人类乳头瘤病毒 (HPV) 疫苗接种率和完成率. 这种以社区为基础的参与式研究方法有望改善青少年接种疫苗.
科学领域:
- 公共卫生
- 预防医学
- 疫苗学
背景情况:
- 人类乳头瘤病毒 (HPV) 疫苗接种对于预防HPV相关癌症至关重要.
- 在未达到最佳水平的HPV疫苗接种需要创新的策略来提高青少年的免疫率.
- 基于社区的参与性研究提供了一种解决公共卫生挑战的新方法.
研究的目的:
- 评估基于社区的参与式研究方法"训练营翻译" (BCT) 对HPV疫苗接种的影响.
- 将使用BCT的诊所与对照诊所的HPV疫苗接种率进行比较.
- 评估BCT在增加HPV疫苗启动和完成方面的有效性.
主要方法:
- 在科罗拉多州的6个儿科诊所进行了准实验性匹配病例对照研究.
- 在6个月的BCT过程中,提供者,工作人员,家长和青少年患者共同设计了HPV疫苗接种信息和活动.
- 在干预和对照诊所中,使用层次逻辑回归模型比较HPV疫苗接种率.
主要成果:
- 在干预诊所,HPV疫苗发射率从45. 9%增加到56. 7%,在对照诊所,从44. 6%增加到52. 8%.
- 在两组中,HPV疫苗完成率也增加,在干预诊所观察到更大的改善.
- 多变量分析显示,与对照组相比,干预诊所的HPV疫苗启动率 (aOR=1. 80) 和完成率 (aOR=1. 72) 显著提高.
结论:
- 训练营翻译 (BCT) 是一种有效的基于社区的参与式研究方法,用于提高HPV疫苗接种率.
- 在临床环境中,BCT方法显著提高了青少年免疫率.
- 进一步实施BCT可能有助于实现更高的HPV疫苗覆盖率,并减少与HPV相关的疾病负担.
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