试点研究使用光度囊对疑似非上部胃肠道出血的患者进行分层治疗
Markus Brand1, Gina Vogt1, Alexander Hann1
1Medical Department II - Gastroenterology, University Hospital Würzburg, Würzburg, Germany.
光度囊检查 (PCE) 有效地识别了可疑患有非静脉上胃肠道出血 (NVUGIH) 的患者,这些患者可以安全地避免紧急内镜检查,从而改善了患者的分层.
科学领域:
- 胃肠病学
- 医疗器械
- 诊断成像
背景情况:
- 目前的指导方针建议在怀疑非的上胃肠道出血 (NVUGIH) 的血液动力稳定的患者中提前进行内镜检查.
- 需要改进的方法来分层患者并优化内镜手术的时间.
研究的目的:
- 评估新型光度囊检查 (PCE) 对疑似NVUGIH患者分层的有用性.
- 确定PCE是否可以区分需要紧急内镜的患者和符合选择性手术的患者.
主要方法:
- 这项前性研究涉及四个中心的73名疑似NVUGIH患者.
- 患者接受了PCE. 阳性结果导致12小时内紧急食管胃管腺镜检查 (EGD);负面结果允许选择性EGD在48-96小时内进行PPI治疗.
- 主要终点是 PCE 结果为负的组中避免早期内镜检查的比率.
主要成果:
- 光度囊检查 (PCE) 显示出100%的灵敏度和负预测值,排除了活跃出血.
- 只有两个患者需要紧急手术,而有95. 1%的PCE结果是避免的.
- 没有报告与PCE或随访期相关的并发症.
结论:
- 光度囊检查 (PCE) 是一种快速,易于使用的工具,用于疑似非的上胃肠道出血 (NVUGIH).
- PCE有效地识别出可以安全推迟紧急内镜的患者,允许选择性手术和优化资源分配.
- 在上胃肠道出血的情况下,这种方法提高了患者的分层和管理.
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