根据年龄,性别和疾病发病时的严重程度来评估角质的自然进展
Onur Ozalp1, Mustafa Kemal Ozaslan1, Fatih Apaydin1
1Eskişehir Osmangazi University, Faculty of Medicine, Department of Ophthalmology, Eskişehir, Turkey.
Cornea
|September 3, 2025
概括
随着年龄的增长,角质 (KC) 的进展会减缓,但许多老年人仍然会遇到这种情况. 由于癌症进展速度较快,年轻患者和老年患者需要密切监测.
科学领域:
- 眼科 眼科
- 角膜疾病
- 视觉科学
背景情况:
- 角膜 (KC) 是一种影响视力的渐进性角膜.
- 了解KC的进展模式对于及时干预和管理至关重要.
- 年龄和疾病严重程度是影响KC自然史的关键因素.
研究的目的:
- 为了研究形的自然进展 (KC).
- 分析年龄,性别和最初的疾病严重程度如何影响KC的进展.
- 确定不同患者群体和KC严重程度的进展率和进展时间.
主要方法:
- 对503名KC患者的949只眼睛进行了回顾性分析,并进行了至少一年的随访.
- 使用Pentacam数据和贝林ABCD进展显示器进行进展评估.
- 根据年龄组和TKC严重程度对患者进行分类.
主要成果:
- 随着年龄的增长,KC的进展显著下降,但在35岁以上的患者中,44. 3%的患者仍有进展.
- 年龄较小的患者 (≤18岁) 患病率最高 (86. 4%).
- 在老年患者 (≥35岁) 中,晚期的KC (TKC3- 4) 显著增加了进展风险,并缩短了进展时间.
结论:
- 虽然随着年龄的增长,KC的进展通常会减缓,但很大一部分老年人仍然面临风险.
- 年轻人和老年患者在呈现时需要谨慎监测.
- 早期检测和持续的随访对于所有年龄组的角质进展的管理至关重要.
相关概念视频
Glaucoma: Overview
745
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
745
Open Angle Glaucoma: Treatment
557
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Drugs such as carbonic anhydrase inhibitors, α2- and...
557
Angle Closure Glaucoma: Treatment
669
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
669


