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Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies01:22

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

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The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
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Rheumatic heart disease (RHD) management can be divided into two main strategies: prevention and long-term management.Primary PreventionPrimary prevention focuses on timely diagnosis and management of group A streptococcal pharyngitis to prevent acute rheumatic fever. The most widely used antibiotic for treating this condition is intramuscular benzathine penicillin G.Acute Rheumatic Fever TreatmentThe primary treatment goal for a patient diagnosed with acute rheumatic fever is to suppress the...
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Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
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The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
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  2. 男性的性别,糖尿病和未接种疫苗的状态是2019年冠状病毒病患者的恶化因素:在日本北関東地區的单中心分析
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  2. 男性的性别,糖尿病和未接种疫苗的状态是2019年冠状病毒病患者的恶化因素:在日本北関東地區的单中心分析

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Glycemic Impact on Knee Osteoarthritis Symptoms on Physical, Radiographic, and Inflammatory Markers among Individuals Aged 50 and Over with Diabetes
07:22

Glycemic Impact on Knee Osteoarthritis Symptoms on Physical, Radiographic, and Inflammatory Markers among Individuals Aged 50 and Over with Diabetes

Published on: March 7, 2025

370

男性的性别,糖尿病和未接种疫苗的状态是2019年冠状病毒病患者的恶化因素:在日本北関東地區的单中心分析

Fuminori Taniguchi1, Hironobu Komine1, Kohei Morikawa1

  • 1Division of Rheumatology and Clinical Immunology, Department of Medicine, Jichi Medical University, Japan.

Internal medicine (Tokyo, Japan)
|September 3, 2025

在PubMed 上查看摘要

概括
此摘要是机器生成的。

在Omicron变种期间,风湿性疾病患者的COVID-19结果通常是有利的. 男性性别,缺乏疫苗接种和糖尿病被确定为2019年严重冠状病毒疾病的危险因素.

关键词:
美国奥米克朗变种葡萄糖类糖尿病多变量逻辑回归分析风湿性疾病接种疫苗

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科学领域:

  • 关节病学
  • 传染性疾病
  • 公共卫生

背景情况:

  • 患有类风湿性疾病的患者可能面临COVID-19等传染性疾病的严重后果的风险.
  • 欧米克朗变种期间在免疫力低下的人群中对COVID-19的管理提出了独特的挑战.

研究的目的:

  • 鉴定 2019 年新冠肺炎 (COVID-19) 患者病情恶化的风险因素.
  • 在Omicron变种激增期间分析风湿病患者的COVID-19结果.

主要方法:

  • 在2022年1月至2023年12月期间对78名被诊断患有COVID-19的风湿性疾病的患者进行了回顾性研究.
  • 收集的数据包括人口统计,风湿性疾病细节,疫苗接种情况,并发症,COVID-19严重程度和结果.
  • 用多变量逻辑回归分析来确定中度至危急的COVID-19的重大风险因素.

主要成果:

  • 大多数患者 (78.2%) 患有轻度的COVID-19;然而,21.8%的患者患有中度至危急的疾病.
  • 中度至危急的COVID-19的重要危险因素包括男性性别 (p=0.012),未接种疫苗状态 (p=0.031) 和糖尿病 (p=0.018).
  • 在多变量分析中,没有发现特定的血液检测结果是严重性预测指标.

结论:

  • 大多数患有风湿性疾病和COVID-19的患者在Omicron变种期间获得了良好的结果.
  • 有效管理伴随疾病,特别是糖尿病,促进疫苗接种对于预防严重的COVID-19在这个人群中至关重要.